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Glossary of Terms

FDA Statement: “Lipo-dissolve is not FDA approved for any use...we are not aware of any [PC] or [DC] injectable products that could be used off-label in lipo-dissolve procedures”

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Active Ingredient – The component of a drug that provides the "pharmacological activity" that causes an effect on the structure or function of the body. Without the active ingredient the drug could not produce the intended effect. (fda.gov)

Compounding Pharmacy – A specific type of pharmacy that prepares a specialized drug product to fill an individual patient prescription authorized by a physician when an approved drug cannot be used for personal reasons of the patient (i.e. the patient is allergic to a certain drug). According to the FDA, unless absolutely necessary, patients are better served when taking commercially manufactured drugs that have been scientifically tested and their safety and efficacy has been proven with sufficient standards. (fda.gov)

Homeopathic Agents – Substances sometimes used in mesotherapy based on the "law of similars". The belief is that substances that induce sickness in healthy people will have curative effects when given in diluted quantities to sick people who exhibit the same symptoms. (National Center for Homeopathy)

Inflammatory response – The immune system's normal response to abnormal stimulation caused by, in the case of lipo-dissolve, a biological substance. (Wikipedia.com)

Injection Lipolysis – Lipolysis is the scientific term for the breakdown of fat molecules (Medline). Injection Lipolyisis therefore refers to the breakdown of fat through injections of external substances.

Localized Fat Deposit – Small collections of fat cells only concentrated in defined areas of the body.

Lipo-dissolve – A term used to refer to the procedure in which phosphatidylcholine and deoxycholate are injected into the middle layer of the skin as a way to lyse fat cells.

Meso "Cocktail" – A term used for the combination of substances injected during the mesotherapy procedure. Often includes a mixture of homeopathic agents, pharmaceuticals medicines, vitamins, minerals and amino acids.

Mesoderm – The middle layer of skin consisting of fat cells and connective tissue.

Mesotherapy – Medical procedure in which a mixture of homeopathic agents, pharmaceuticals, vitamins, minerals and amino acids are injected into the mesoderm in order to treat a variety of conditions including chronic pain, psoriasis, & spot weight loss.

Micro-Injection – Very small injections of one or two drops of liquid, often given many times over a treatment area.

Off-Label – An FDA-approved product used by a licensed physician for something other than those indications for which the drug is currently approved.

PCDC – Abbreviation used for the combination of Phosphatidylcholine (PC) and Deoxycholate (DC). Phosphatidylcholine is a phospholipid of soy lecithin and is responsible for emulsifying the fat we consume in our diet for absorption. Deoxycholate is a bile salt that functions to make the phosphatidylcholine soluble in water. The two substances in combination have been termed a "drug" in numerous media articles by a spokesperson of the FDA, who has stated "these are unapproved drugs for unapproved uses" *

Phosphoglyceride – Lipid molecules making up cell membranes composed of two fatty acid molecules attached to one glycerol molecule. There are numerous phosphoglycerides (phosphatidylcholine being one of them) each defined by their distribution of components which is unique to not only different organisms, but to different tissues of the same organism, and often to even individual cells of the same tissue.

Prospective Placebo Controlled Study – A prospective study is one that has the treatments and evaluations planned before the study starts. A placebo is an inactive substance (sugar pill) that appears to look identical to the active treatment. Participants in a prospective placebo controlled study are usually randomly assigned to receive either the placebo or the active substance. Since the two substances look identical, neither the participant nor the doctor know which treatment the participant receives. This will illustrate the efficacy of the drug and that it is the drug that is eliciting a response, not the placebo.

Prospective Non-Placebo Controlled Study – A non-placebo controlled study is one in which an active treatment is given and both the participant and the doctor know that it is the active drug. In turn, one cannot have a control to compare the results.

Retrospective Study – Making conclusions from pre-existing data. In the case of lipo-dissolve, a restrospective study involves using results, or interviewing patients to draw conclusions from those who have already undergone the procedure (medicinenet.com).

Solubilize – To increase the ability of a solid substance to dissolve in solution. (Medlineplus.net)

Subcutaneous Injection – Injection of a substance after insertion of the needle under the skin. (Medicinenet.com)

* Riley, Karen "FDA's statement to Headline 3 regarding lipo-dissolve". KVBC. 20 Sept 2007

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